{"id":23825,"date":"2023-03-08T12:21:51","date_gmt":"2023-03-08T17:21:51","guid":{"rendered":"https:\/\/genomequebec.com\/?post_type=service&#038;p=23825"},"modified":"2024-05-13T10:07:53","modified_gmt":"2024-05-13T14:07:53","slug":"methylation","status":"publish","type":"service","link":"https:\/\/genomequebec.com\/en\/technological-services\/centre-dexpertise-et-de-services-2\/methylation\/","title":{"rendered":"Methylation"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">Quantitative Methylation Analysis of Genomic DNA<\/h2>\n\n\n\n<p>DNA methylation plays an important role in the regulation of gene expression. Following the treatment of genomic DNA (gDNA) with sodium bisulfite, the non-methylated cytosine (C) residues are converted to uracil (U) residues (which are then converted to thymine (T) residues after amplification). Several technologies allow the measurement of the C\/T ratios of CpG sites (which correspond to the methylation level) in targeted regions or in the entire genome.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Available Technologies<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/cesgq.com\/en-methylation-1\" target=\"_blank\" rel=\"noopener\">Agena\u00ae EpiTYPER\u00ae<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/cesgq.com\/en-methylation-3\" target=\"_blank\" rel=\"noopener\">Illumina\u00ae Infinium Methylation<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/genomequebec.com\/services-technologiques\/methylation\/analyse-de-methylation-dechantillons-ffpe\/\" data-type=\"URL\" data-id=\"https:\/\/genomequebec.com\/services-technologiques\/methylation\/analyse-de-methylation-dechantillons-ffpe\/\">Methylation FFPE Analysis<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/genomequebec.com\/en\/technological-services\/sequencing\/illumina-technologies\/\" data-type=\"URL\" data-id=\"https:\/\/genomequebec.com\/en\/technological-services\/sequencing\/illumina-technologies\/\">Whole Genome Bisulfite sequencing (WGBS)<\/a><\/li>\n<\/ul>\n","protected":false},"featured_media":20489,"parent":26647,"menu_order":0,"template":"","class_list":["post-23825","service","type-service","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/service\/23825","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/service"}],"about":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/types\/service"}],"up":[{"embeddable":true,"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/service\/26647"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/media\/20489"}],"wp:attachment":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/media?parent=23825"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}