{"id":16755,"date":"2019-01-15T00:00:00","date_gmt":"2019-01-15T05:00:00","guid":{"rendered":"https:\/\/genomequebec.com\/actualites-et-publications\/breast-cancer-a-simple-saliva-test-to-evaluate-the-risk-of-developing-the-disease\/"},"modified":"2019-01-15T00:00:00","modified_gmt":"2019-01-15T05:00:00","slug":"breast-cancer-a-simple-saliva-test-to-evaluate-the-risk-of-developing-the-disease","status":"publish","type":"post","link":"https:\/\/genomequebec.com\/en\/news-and-publications\/breast-cancer-a-simple-saliva-test-to-evaluate-the-risk-of-developing-the-disease\/","title":{"rendered":"Breast cancer: a simple saliva test to evaluate the risk of developing the disease"},"content":{"rendered":"<p>G\u00e9nome Qu\u00e9bec is pleased to highlight the unprecedented advances of Prof.\u00a0Jacques Simard\u2019s work, co-author of two important studies on the risk of developing breast cancer.<\/p>\n<p>\u00a0<\/p>\n<p>Thanks to this work, a simple saliva test could help to gauge, with unprecedented accuracy, a woman\u2019s risk of developing breast cancer during her lifetime, according to an international study published today. By combining a person\u2019s genetic profile obtained through a saliva sample with a statistical model that takes into account family history, hormonal factors and lifestyle habits, the researchers were able to estimate each woman\u2019s overall risk for breast cancer, paving the way for personalized screening protocols for the disease.<\/p>\n<p>\u201cMany hundreds of researchers around the world pooled the DNA samples they had collected through their respective projects and conducted genomic analyses on 94,000 women who had had breast cancer and another 75,000 women who were part of a control group,\u201d explains one of the study\u2019s leaders, Jacques Simard, Canada Research Chair in Oncogenetics at Universit\u00e9 Laval and researcher at the Genomics Center of the CHU de Qu\u00e9bec-Universit\u00e9 Laval Research Center. Through sophisticated statistical analyses, we developed a breast cancer risk score that includes 313 genetic variants and then validated it on nearly 220,000 women.\u201d<\/p>\n<p>\u00a0<\/p>\n<p><a href=\"https:\/\/www.genomequebec.com\/DATA\/COMMUNIQUE\/341_en~v~Breast_Cancer_-_Researchers_develop_the_most_accurate_risk-prediction_model_to_date.pdf\" target=\"_blank\" rel=\"noopener\">Read the press release<\/a><br \/>Read the article in <a href=\"https:\/\/www.nature.com\/articles\/s41436-018-0406-9\" target=\"_blank\" rel=\"noopener\"><em>Genetics in Medicine<\/em><\/a><em><br \/><\/em>Read the article in <a href=\"https:\/\/www.cell.com\/ajhg\/fulltext\/S0002-9297(18)30405-1#secsectitle0090\" target=\"_blank\" rel=\"noopener\"><em>The American Journal of Human Genetics<\/em><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>G\u00e9nome Qu\u00e9bec is pleased to highlight the unprecedented advances of Prof.\u00a0Jacques Simard\u2019s work, co-author of two important studies on the risk of developing breast cancer. \u00a0 Thanks to this work,&hellip;<\/p>\n","protected":false},"author":1,"featured_media":16141,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[294],"tags":[],"class_list":["post-16755","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-nouvelles"],"acf":[],"_links":{"self":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/posts\/16755","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/comments?post=16755"}],"version-history":[{"count":0,"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/posts\/16755\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/media\/16141"}],"wp:attachment":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/media?parent=16755"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/categories?post=16755"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/tags?post=16755"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}