{"id":16637,"date":"2015-07-09T00:00:00","date_gmt":"2015-07-09T04:00:00","guid":{"rendered":"https:\/\/genomequebec.com\/actualites-et-publications\/montreal-researchers-discover-a-new-crucial-gene-associated-with-leukodystrophies\/"},"modified":"2015-07-09T00:00:00","modified_gmt":"2015-07-09T04:00:00","slug":"montreal-researchers-discover-a-new-crucial-gene-associated-with-leukodystrophies","status":"publish","type":"post","link":"https:\/\/genomequebec.com\/en\/news-and-publications\/montreal-researchers-discover-a-new-crucial-gene-associated-with-leukodystrophies\/","title":{"rendered":"Montr\u00e9al researchers discover a new crucial gene associated with leukodystrophies"},"content":{"rendered":"<p><span>An international research team, led by Dr. Genevi\u00e8ve Bernard from the Research Institute of the\u00a0<\/span><span class=\"xn-org\">McGill University<\/span><span>\u00a0Health Centre (RI-MUHC) and Dr.\u00a0<\/span><span class=\"xn-person\">Benoit Coulombe<\/span><span>\u00a0from the Institut de recherches cliniques de Montr\u00e9al (IRCM), has identified a new gene associated with 4H leukodystrophy, one of the common forms of the disease. Their findings have been published in the journal\u00a0<\/span><em>Nature Communications<\/em><span>\u00a0this week.<\/span><\/p>\n<p><span>&#8220;We are finally starting to better understand this terrible disease. By discovering mutations on this new gene called POLR1C, which account for nearly 10 per cent of cases with this type of leukodystrophy, we now have a better idea of the impact they have on nervous system cells,&#8221; says one of the principal co-authors, Dr. Bernard, neurologist at the Montreal Children&#8217;s Hospital of the MUHC (MCH-MUHC) at the Glen site and assistant professor of Neurology and Neurosurgery at McGill\u00a0University.<\/span><\/p>\n<p>\u00a0<\/p>\n<p>To learn more:\u00a0<\/p>\n<p><a href=\"http:\/\/www.newswire.ca\/en\/story\/1567877\/a-glimmer-of-hope-for-patients-with-leukodystrophies-montreal-researchers-discover-a-new-crucial-gene-associated-with-these-orphan-diseases\" target=\"_blank\" rel=\"noopener\">http:\/\/www.newswire.ca\/en\/story\/1567877\/a-glimmer-of-hope-for-patients-with-leukodystrophies-montreal-researchers-discover-a-new-crucial-gene-associated-with-these-orphan-diseases<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>An international research team, led by Dr. Genevi\u00e8ve Bernard from the Research Institute of the\u00a0McGill University\u00a0Health Centre (RI-MUHC) and Dr.\u00a0Benoit Coulombe\u00a0from the Institut de recherches cliniques de Montr\u00e9al (IRCM), has&hellip;<\/p>\n","protected":false},"author":1,"featured_media":15693,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[294],"tags":[],"class_list":["post-16637","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-nouvelles"],"acf":[],"_links":{"self":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/posts\/16637","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/comments?post=16637"}],"version-history":[{"count":0,"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/posts\/16637\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/media\/15693"}],"wp:attachment":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/media?parent=16637"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/categories?post=16637"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/tags?post=16637"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}