{"id":16593,"date":"2014-08-04T00:00:00","date_gmt":"2014-08-04T04:00:00","guid":{"rendered":"https:\/\/genomequebec.com\/actualites-et-publications\/a-montreal-invention-to-detect-genetic-anomalies\/"},"modified":"2014-08-04T00:00:00","modified_gmt":"2014-08-04T04:00:00","slug":"a-montreal-invention-to-detect-genetic-anomalies","status":"publish","type":"post","link":"https:\/\/genomequebec.com\/en\/news-and-publications\/a-montreal-invention-to-detect-genetic-anomalies\/","title":{"rendered":"A Montr\u00e9al invention to detect genetic anomalies"},"content":{"rendered":"<p><strong>Speedier diagnosis of diseases such as cancer likely thanks <\/strong><strong>to new DNA analysis technique<\/strong><\/p>\n<p>\u00a0<\/p>\n<p>Dr. Rob Sladek of the McGill University and G\u00e9nome Qu\u00e9bec Innovation Centre was part of Pr. Sabrina Leslie&#8217;s team from McGill University who developed a breakthrough technique for massive parallel genomic analysis of long DNA molecules. This technical breakthrough should result in speedier diagnosis of cancer and various pre-natal conditions.\u00a0<\/p>\n<p>The key discovery, which is described online this week in the Proceedings of the National Academy of Sciences (PNAS), lies in a new tool developed by Professors Sabrina Leslie and Walter Reisner of McGill\u2019s Physics Department and their collaborator Dr. Rob Sladek of the G\u00e9nome Qu\u00e9bec Innovation Centre. It allows researchers to load long strands of DNA into a tunable nanoscale imaging chamber in ways that maintain their structural identity and under conditions that are similar to those found in the human body.<\/p>\n<p>This newly developed &#8220;Convex Lens-Induced Confinement&#8221; (CLIC) will permit researchers to rapidly map large genomes while at the same time clearly identifying specific gene sequences from single cells with single-molecule resolution, a process that is critical to diagnosing diseases like cancer.<\/p>\n<p><a href='\/wp-content\/uploads\/data\/nouvelle\/183_en.pdf' download>T\u00e9l\u00e9charger le document<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Speedier diagnosis of diseases such as cancer likely thanks to new DNA analysis technique \u00a0 Dr. Rob Sladek of the McGill University and G\u00e9nome Qu\u00e9bec Innovation Centre was part of&hellip;<\/p>\n","protected":false},"author":1,"featured_media":15537,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","footnotes":""},"categories":[294],"tags":[],"class_list":["post-16593","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-nouvelles"],"acf":[],"_links":{"self":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/posts\/16593","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/comments?post=16593"}],"version-history":[{"count":0,"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/posts\/16593\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/media\/15537"}],"wp:attachment":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/media?parent=16593"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/categories?post=16593"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/tags?post=16593"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}