{"id":25748,"date":"2023-05-24T10:17:09","date_gmt":"2023-05-24T14:17:09","guid":{"rendered":"https:\/\/genomequebec.com\/financed-project\/chemical-genetic-screens-for-tdp-43-modifiers-and-amyotrophic-lateral-sclerosis-therapeutics\/"},"modified":"2023-05-24T10:26:53","modified_gmt":"2023-05-24T14:26:53","slug":"chemical-genetic-screens-for-tdp-43-modifiers-and-amyotrophic-lateral-sclerosis-therapeutics","status":"publish","type":"financed-project","link":"https:\/\/genomequebec.com\/en\/funded-projects\/chemical-genetic-screens-for-tdp-43-modifiers-and-amyotrophic-lateral-sclerosis-therapeutics\/","title":{"rendered":"Chemical genetic screens for TDP-43 modifiers and amyotrophic lateral sclerosis therapeutics"},"content":{"rendered":"<p style=\"text-align: justify;\">Pierre Drapeau and his team at Universit\u00e9 of Montr\u00e9al have recently discovered mutations in the gene (TDP-43) associated with amyotrophic lateral sclerosis (ALS). The team will use zebrafish, a model system for the study of neuromotor diseases. Because the embryos are small, they can be obtained in large numbers and develop motor behaviors within a day; it is possible to screen thousands of compounds to restore motricity.<\/p>\n<p style=\"text-align: justify;\">By using this innovative model, Professor Drapeau\u2019s team will try to develop new ALS therapeutics approaches, a disease for which no effective treatment is available.<\/p>\n<p style=\"text-align: justify;\">\u00a0<\/p>\n<p style=\"text-align: justify;\"><strong>Co-applicant:<\/strong><\/p>\n<table style=\"width: 735px;\" border=\"0\" cellspacing=\"0\" cellpadding=\"0\">\n<colgroup>\n<col span=\"2\" width=\"112\" \/>\n<col width=\"511\" \/><\/colgroup>\n<tbody>\n<tr>\n<td class=\"xl65\" width=\"112\" height=\"19\">Edor<\/td>\n<td class=\"xl65\" width=\"112\">Kabashi<\/td>\n<td class=\"xl66\" width=\"511\">Universit\u00e9 de Montr\u00e9al<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"text-align: justify;\">\u00a0<\/p>\n","protected":false},"featured_media":0,"template":"","class_list":["post-25748","financed-project","type-financed-project","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/financed-project\/25748","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/financed-project"}],"about":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/types\/financed-project"}],"wp:attachment":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/media?parent=25748"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}