{"id":25692,"date":"2023-05-24T10:16:44","date_gmt":"2023-05-24T14:16:44","guid":{"rendered":"https:\/\/genomequebec.com\/financed-project\/comparative-and-functional-genomics-of-the-human-pathogen-cryptococcus-neoformans\/"},"modified":"2023-05-24T10:26:24","modified_gmt":"2023-05-24T14:26:24","slug":"comparative-and-functional-genomics-of-the-human-pathogen-cryptococcus-neoformans","status":"publish","type":"financed-project","link":"https:\/\/genomequebec.com\/en\/funded-projects\/comparative-and-functional-genomics-of-the-human-pathogen-cryptococcus-neoformans\/","title":{"rendered":"Comparative and Functional Genomics of the Human Pathogen <i>Cryptococcus Neoformans<\/i>"},"content":{"rendered":"<p>An outbreak in British Columbia of a sometimes fatal lung and central nervous system infection, caused by the fungus <i>Cryptococcus neoformans<\/i> provided part of the incentive for this project. Over sixty people in the province have had <i>Cryptococcus<\/i> lung infections and these people reportedly had healthy immune systems. Worldwide, there are three varieties of this fungus &#8211; <i>C. neoformans var. neoformans, grubii<\/i> and <i>gattii<\/i>. Researchers in BC are sequencing the <i>gattii<\/i> variety and are comparing it with the genomes of the other two varieties to understand how this fungus causes disease. This comparison will help the team understand why the <i>gattii<\/i> variety tends to attack people with an intact immune system, while the other two varieties attack immuno-compromised individuals. Gaining a thorough comprehension of the <i>Cryptococcus genus<\/i> can contribute to the development of new antifungal drugs and better ways to diagnose fungal infections. <\/p>\n<p>This project involves scientists from the University of British Columbia, the BC Cancer Agency and the BC <i>Cryptococcus<\/i> Working Group.<\/p>\n<p>A SUMMARY OF THE OUTCOMES FROM THIS COMPLETED PROJECT IS CURRENTLY BEING CONSTRUCTED.<br \/>\nPLEASE CHECK THIS SITE AGAIN FOR AN UPDATE ON PROJECT RESULTS.<\/p>\n","protected":false},"featured_media":0,"template":"","class_list":["post-25692","financed-project","type-financed-project","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/financed-project\/25692","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/financed-project"}],"about":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/types\/financed-project"}],"wp:attachment":[{"href":"https:\/\/genomequebec.com\/en\/wp-json\/wp\/v2\/media?parent=25692"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}